Tg(Cd4-TcraDN32D3)1Aben
Transgene Detail

Summary

• Symbol: Tg(Cd4-TcraDN32D3)1Aben
• Name: transgene insertion 1, Albert Bendelac
• MGI ID: MGI:4880641
• Synonyms: Tg-Valpha18-Jalpha18
• Transgene: Tg(Cd4-TcraDN32D3)1Aben Location: unknown
• Alliance: Tg(Cd4-TcraDN32D3)1Aben page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Cd4-TcraDN32D3)1Aben expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tcra (MGI:98553)

• Mutation details: The Valpha14-Jalpha18 transgene was developed containing prearranged Valpha14-Jalpha18 T cell receptor (TCR) cDNA (DN32.D3 hybridoma line) downstream of CD4 promoter/enhancer elements. Line 1 was generated. (J:127620)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:127620 Griewank K, et al., Homotypic interactions mediated by slamf1 and slamf6 receptors control NKT cell lineage development. Immunity. 2007 Nov;27(5):751-62
• All: 20 reference(s)