Pitx2^tm1.1Mbf
Targeted Allele Detail

Summary

• Symbol: Pitx2^tm1.1Mbf
• Name: paired-like homeodomain transcription factor 2; targeted mutation 1.1, Milena B Furtado
• MGI ID: MGI:4880738
• Synonyms: Pitx2^flox
• Gene: Pitx2 Location: Chr3:128993527-129013240 bp, + strand Genetic Position: Chr3, 57.84 cM
• Alliance: Pitx2^tm1.1Mbf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:167616
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 5, and a neo cassette with a 3' loxP site was inserted downstream of exon 5. (J:167616)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pitx2 Mutation: 39 strains or lines available

References

• Original: J:167616 Furtado MB, et al., Characterization of Pitx2c expression in the mouse heart using a reporter transgene. Dev Dyn. 2011 Jan;240(1):195-203
• All: 2 reference(s)