Ripply3^tm1Sjt
Targeted Allele Detail

Summary

• Symbol: Ripply3^tm1Sjt
• Name: ripply transcriptional repressor 3; targeted mutation 1, Shinji Takada
• MGI ID: MGI:4880754
• Gene: Ripply3 Location: Chr16:94129281-94137794 bp, + strand Genetic Position: Chr16, 55.17 cM, cytoband C4
• Alliance: Ripply3^tm1Sjt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:167713
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1 - 3 were replaced with an IRES-lacZ-pgk-neo cassette via homologous recombination. RT-PCR analysis confirmed the absence of expression in homozygous embryos at E9.5. (J:167713)

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	17 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ripply3 Mutation: 9 strains or lines available

References

• Original: J:167713 Okubo T, et al., Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice. Development. 2011 Jan;138(2):339-48
• All: 5 reference(s)