Tmem100^tm1.2Yjl
Targeted Allele Detail

Summary

• Symbol: Tmem100^tm1.2Yjl
• Name: transmembrane protein 100; targeted mutation 1.2, Young J Lee
• MGI ID: MGI:4881485
• Synonyms: Tmem100^SIBN-1loxP
• Gene: Tmem100 Location: Chr11:89921174-89927334 bp, + strand Genetic Position: Chr11, 54.75 cM
• Alliance: Tmem100^tm1.2Yjl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166956
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT flanked cassette containing a splice donor/acceptor site, an IRES, a lacZ gene and a neo resistance gene was inserted into intron 2 and exon 3 containing the entire coding region was floxed via homologous recombination. Cre mediated recombination removed exon 3. The selection and reporter cassette remains intact. (J:166956)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem100 Mutation: 15 strains or lines available

References

• Original: J:166956 Moon EH, et al., Generation of mice with a conditional and reporter allele for Tmem100. Genesis. 2010 Nov;48(11):673-8
• All: 1 reference(s)