S1pr2^tm2Ytak
Targeted Allele Detail

Summary

• Symbol: S1pr2^tm2Ytak
• Name: sphingosine-1-phosphate receptor 2; targeted mutation 2, Yoh Takuwa
• MGI ID: MGI:4881825
• Synonyms: S1P2^LacZ
• Gene: S1pr2 Location: Chr9:20877248-20888089 bp, - strand Genetic Position: Chr9, 7.68 cM
• Alliance: S1pr2^tm2Ytak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:168060
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• The coding exon was replaced with a lacZ and neo cassette. (J:168060)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any S1pr2 Mutation: 48 strains or lines available

References

• Original: J:168060 Du W, et al., S1P(2), the G protein-coupled receptor for sphingosine-1-phosphate, negatively regulates tumor angiogenesis and tumor growth in vivo in mice. Cancer Res. 2010 Jan 15;70(2):772-81
• All: 5 reference(s)