Tg(Hoxb8-cre)1403Uze
Transgene Detail

Summary

• Symbol: Tg(Hoxb8-cre)1403Uze
• Name: transgene insertion 1403, University of Zurich
• MGI ID: MGI:4881836
• Synonyms: Hoxb8-Cre^tg+
• Transgene: Tg(Hoxb8-cre)1403Uze Location: unknown
• Alliance: Tg(Hoxb8-cre)1403Uze page

Transgene origin

• Strain of Origin: C57BL/6 x DBA/2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Hoxb8-cre)1403Uze expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Hoxb8 (MGI:96189)

• Mutation details: The construct contained a cre recombinase cassette and bovine poly(A) sequence inserted in-frame downstream of the Hoxb8 ATG site. Fertilized early-stage C57BL/6 x DBA/2 oocytes were injected with the linearized construct, and four founders were obtained. Founders were mated to generated transgenic lines, two of which (1403 and 1404) exhibited the expected expression pattern on a gross scale at E9.5 and E11.5. Line 1403 carries a single copy of the transgene and was characterized in detail. (J:168059)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hoxb8 (mouse) Summary of all recombinase alleles driven by Hoxb8. Comparative matrix view of recombinase activities Alliance mouse Hoxb8 gene page

Expression

In Mice Carrying this Mutation:

16 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:168059 Witschi R, et al., Hoxb8-Cre mice: A tool for brain-sparing conditional gene deletion. Genesis. 2010 Oct 1;48(10):596-602
• All: 24 reference(s)