Perp^tm2Att
Targeted Allele Detail

Summary

• Symbol: Perp^tm2Att
• Name: PERP, TP53 apoptosis effector; targeted mutation 2, Laura D Attardi
• MGI ID: MGI:4882063
• Synonyms: Perp^fl
• Gene: Perp Location: Chr10:18720819-18732821 bp, + strand Genetic Position: Chr10, 7.97 cM, cytoband A2
• Alliance: Perp^tm2Att page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:167545
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Not Specified
• Mutation details: A targeting vector was designed to insert a loxP site downstream of exon 1 and a second loxP site downstream of exon 3 of the PERP, TP53 apoptosis effector (Perp) gene. (J:169826)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Perp Mutation: 9 strains or lines available

References

• Original: J:167545 Beaudry VG, et al., Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis. PLoS Genet. 2010;6(10):e1001168
• All: 4 reference(s)