Tg(Ddx4-cre/ERT2)1Dcas
Transgene Detail

Summary

• Symbol: Tg(Ddx4-cre/ERT2)1Dcas
• Name: transgene insertion 1, Diego H Castrillon
• MGI ID: MGI:4882088
• Synonyms: Vasa-Cre, Vasa-Cre^ERT2
• Transgene: Tg(Ddx4-cre/ERT2)1Dcas Location: unknown
• Alliance: Tg(Ddx4-cre/ERT2)1Dcas page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(Ddx4-cre/ERT2)1Dcas expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Ddx4

• Mutation details: The transgene construct consists of the Ddx4 (Vasa) promoter driving the expression of a cre/ERT2 cassette. The purified construct was injected into FVB/N oocytes. Transgenic animals were produced with one line showing high expression in the testis and ovary, but not in any somatic tissues, was selected for further analysis. (J:138697)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ddx4 (species not specified) Summary of all recombinase alleles driven by Ddx4. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:138697 John GB, et al., Foxo3 is a PI3K-dependent molecular switch controlling the initiation of oocyte growth. Dev Biol. 2008 Sep 1;321(1):197-204
• All: 12 reference(s)