Tg(Wnt7a-EGFP/cre)#Bhr
Transgene Detail

Summary

• Symbol: Tg(Wnt7a-EGFP/cre)#Bhr
• Name: transgene insertion, Richard R Behringer
• MGI ID: MGI:4882135
• Synonyms: Tg(Wnt7a-EGFP/cre)#Ksk, Wnt7a-Cre
• Transgene: Tg(Wnt7a-EGFP/cre)#Bhr Location: unknown
• Alliance: Tg(Wnt7a-EGFP/cre)#Bhr page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Wnt7a-EGFP/cre)#Bhr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Wnt7a (MGI:98961)

• Mutation details: An IRES-EGFP/cre with an FRT-flanked kanamycin selection cassette was targeted to exon 2 of the Wnt7a locus in BAC RP23-53E13. After homologous recombination in EL250 cells, correctly targeted clones were selected and FRT recombination was induced in cells by arabinose to remove the kanamycin cassette. The linearized BAC was injected into pronuclei of B6SJLF1 hybrid zygotes. Mice express an EGFP-cre fusion gene product. No line numbers are available. (J:167551, J:191769)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Wnt7a (mouse) Summary of all recombinase alleles driven by Wnt7a. Comparative matrix view of recombinase activities Alliance mouse Wnt7a gene page

Expression

In Mice Carrying this Mutation:

25 assay results 3 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Wnt7a-EGFP/cre)#Bhr

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:167551 Winuthayanon W, et al., Uterine epithelial estrogen receptor alpha is dispensable for proliferation but essential for complete biological and biochemical responses. Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19272-7
• All: 31 reference(s)