Mkx^tm1Miu
Targeted Allele Detail

Summary

• Symbol: Mkx^tm1Miu
• Name: mohawk homeobox; targeted mutation 1, Naoyuki Miura
• MGI ID: MGI:4887450
• Gene: Mkx Location: Chr18:6934966-7004779 bp, - strand Genetic Position: Chr18, 4.53 cM
• Alliance: Mkx^tm1Miu page

Mkx^tm1Miu/Mkx^tm1Miu mice show reduced tendon formation

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:167977
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129 x C57BL/6

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion A segment of DNA including exon 3 was replaced with a neo cassette via homologous recombination. (J:167977)

Generation of the Mkx^tm1Miu allele

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mkx Mutation: 28 strains or lines available

References

• Original: J:167977 Kimura W, et al., Irxl1 mutant mice show reduced tendon differentiation and no patterning defects in musculoskeletal system development. Genesis. 2011 Jan;49(1):2-9
• All: 1 reference(s)