Lrfn3^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Lrfn3^{tm1(KOMP)Vlcg}
• Name: leucine rich repeat and fibronectin type III domain containing 3; targeted mutation 1, Velocigene
• MGI ID: MGI:4887760
• Gene: Lrfn3 Location: Chr7:30054939-30062197 bp, - strand Genetic Position: Chr7, 17.41 cM
• Alliance: Lrfn3^{tm1(KOMP)Vlcg} page
• IMPC: Lrfn3 gene page

Mutation origin

• Mutant Cell Lines: 15252A-A12, 15252A-B2, 15252A-E6, 15252A-E7
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 5218bp between positions 30055003-30060220 of Chromosome 7 (Build GRCm39). Western blot analysis confirmed the absence of protein expression in the brain. (J:136110, J:241274)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Lrfn3 Mutation: 24 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 4 reference(s)