Rag2^tm1.1Flv
Targeted Allele Detail

Summary

• Symbol: Rag2^tm1.1Flv
• Name: recombination activating gene 2; targeted mutation 1.1, Richard A Flavell
• MGI ID: MGI:4887836
• Gene: Rag2 Location: Chr2:101455063-101462874 bp, + strand Genetic Position: Chr2, 53.87 cM
• Alliance: Rag2^tm1.1Flv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:168303
• Parent Cell Line: V17 (ES Cell)
• Strain of Origin: BALB/cAnNTac x 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A floxed PGK-neomycin cassette replaced the coding region. Cre-mediated recombination removed the neo cassette. (J:168303)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 6 strains available Cell Lines: 0 lines available
• Carrying any Rag2 Mutation: 119 strains or lines available

Notes

Originally generated in conjunction with Il2rg^tm1.1Flv.

References

• Original: J:168303 Song J, et al., A mouse model for the human pathogen Salmonella typhi. Cell Host Microbe. 2010 Oct 21;8(4):369-76
• All: 97 reference(s)