Tg(Col1a1-Runx2)#Pmt
Transgene Detail

Summary

• Symbol: Tg(Col1a1-Runx2)#Pmt
• Name: transgene insertion, Patrick Matthias
• MGI ID: MGI:4887925
• Synonyms: Runx2^Tg
• Transgene: Tg(Col1a1-Runx2)#Pmt Location: unknown
• Alliance: Tg(Col1a1-Runx2)#Pmt page

Transgene origin

• Strain of Origin: C57BL/6 x BALB/c

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Col1a1-Runx2)#Pmt expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Runx2 (MGI:99829)

• Mutation details: The rat promoter drives chondrocyte expression of the mouse cDNA in osteoblasts. Three high expressing lines (41, 42, and 44) and one low expressing line (27) were generated. (J:78432)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:167992 Hesse E, et al., Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity. J Cell Biol. 2010 Dec 27;191(7):1271-83
• All: 3 reference(s)