Tg(Fabp1-NR1I2)#Wexi
Transgene Detail

Summary

• Symbol: Tg(Fabp1-NR1I2)#Wexi
• Name: transgene insertion, Wen Xie
• MGI ID: MGI:4887981
• Synonyms: FABP-VP-hPXR, VP-hPXR
• Transgene: Tg(Fabp1-NR1I2)#Wexi Location: unknown
• Alliance: Tg(Fabp1-NR1I2)#Wexi page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Fabp1-NR1I2)#Wexi expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  NR1I2 (8856)

  Nr1i2

  (MGI:1337040)

• Mutation details: The rat Fabp1 promoter (nucleotides -596 to +21) was used to drive expression of human NR1I2 in the liver and intestine. The VP16 activation domain of the Herpes simplex virus was fused to the 5' end of the NR1I2 cDNA. (J:105118)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:105118 Gong H, et al., Orphan nuclear receptor pregnane X receptor sensitizes oxidative stress responses in transgenic mice and cancerous cells. Mol Endocrinol. 2006;20(2):279-290
• All: 4 reference(s)