Tg(Vav1-cre)8Cgp
Transgene Detail

Summary

• Symbol: Tg(Vav1-cre)8Cgp
• Name: transgene insertion 8, Cristin G Print
• MGI ID: MGI:4888391
• Synonyms: vavCre8, VC8
• Transgene: Tg(Vav1-cre)8Cgp Location: unknown
• Alliance: Tg(Vav1-cre)8Cgp page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Vav1-cre)8Cgp expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Vav1

• Mutation details: An SV40 intron, cre recombinase cDNA and an SV40 polyA cassette were inserted into a vector behind the Vav1 promoter. The construct was injected into pronuclei to generate transgenic mice. 2 lines, 1 and 8, resulted and both exhibited recombination in the majority of hematopoietic and endothelial cells but very little in other somatic cells. (J:81647)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Vav1 (species not specified) Summary of all recombinase alleles driven by Vav1. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:81647 Georgiades P, et al., vavCre Transgenic mice: A tool for mutagenesis in hematopoietic and endothelial lineages. Genesis. 2002 Dec;34(4):251-6
• All: 1 reference(s)