Tg(Tex101-icre)2Lzj
Transgene Detail

Summary

• Symbol: Tg(Tex101-icre)2Lzj
• Name: transgene insertion 2, Zi-Jian Lan
• MGI ID: MGI:4888565
• Synonyms: Tex101-iCre
• Transgene: Tg(Tex101-icre)2Lzj Location: unknown
• Alliance: Tg(Tex101-icre)2Lzj page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Tex101-icre)2Lzj expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Tex101

• Mutation details: A construct in which the Tex101 promoter fragment was cloned in front of a codon-improved cre cassette with the nuclear localization signal from the SV40 large T antigen and the SV40 polyadenylation signal was microinjected in (C57BL/6 x SJL)F2 fertilized eggs. 3 lines were produced and crossed to ROSA26 reporter mice. In two lines (#1 and #5), ectopic activity was detected (all tested tissues stained), but reporter staining in crosses derived from #2 was robust in the testis with no staining in ovary or other tissues. (Spotty staining on the kidney surface was observed). Line 2 was analyzed in further detail. (J:168353)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tex101 (species not specified) Summary of all recombinase alleles driven by Tex101. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:168353 Lei Z, et al., Postnatal male germ-cell expression of cre recombinase in Tex101-iCre transgenic mice. Genesis. 2010 Dec;48(12):717-22
• All: 1 reference(s)