Tg(Trpv5-cre)#Prae
Transgene Detail

Summary

• Symbol: Tg(Trpv5-cre)#Prae
• Name: transgene insertion, Jeppe Praetorius
• MGI ID: MGI:4888717
• Synonyms: TRPV5-Cre
• Transgene: Tg(Trpv5-cre)#Prae Location: unknown
• Alliance: Tg(Trpv5-cre)#Prae page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Trpv5-cre)#Prae expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Trpv5

• Mutation details: The transgenic construct consisted of a 3.6 kb fragment of the Trpv5 promoter inserted upstream of the cre recombinase coding region. This construct was injected into male pronuclei of B6D2F2 zygotes. Founder line information was not available. Transgenic mice were validated by PCR and immunoblotting with a cre antibody. Recombinase activity was assessed in offspring from crosses of cre transgenics with a floxed Aqp2 line. (J:168534)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Trpv5 (species not specified) Summary of all recombinase alleles driven by Trpv5.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:168534 Hofmeister MV, et al., The TRPV5 Promoter as a Tool for Generation of Transgenic Mouse Models. Adv Exp Med Biol. 2011;704:277-86
• All: 1 reference(s)