Emx2^wndr
Chemically induced Allele Detail

Summary

• Symbol: Emx2^wndr
• Name: empty spiracles homeobox 2; wanderer
• MGI ID: MGI:4888743
• Synonyms: ND87
• Gene: Emx2 Location: Chr19:59447122-59453789 bp, + strand Genetic Position: Chr19, 56.28 cM
• Alliance: Emx2^wndr page

Mutation origin

• Strain of Origin: BALB/c x C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A transversion that results in the amino acid substitution of a stop codon for tyrosine at position 130 (Y130X). (J:168258)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Emx2 Mutation: 24 strains or lines available

Notes

Originally generated from male mice expressing Tg(Mbp-MAPT/lacZ)#Caw.

References

• Original: J:168258 Dwyer ND, et al., A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct emx2 mutant phenotype. Neural Dev. 2011;6:3
• All: 1 reference(s)