Shh^tm2.1Amc
Targeted Allele Detail

Summary

• Symbol: Shh^tm2.1Amc
• Name: sonic hedgehog; targeted mutation 2.1, Andrew P McMahon
• MGI ID: MGI:4889084
• Gene: Shh Location: Chr5:28661838-28672099 bp, - strand Genetic Position: Chr5, 14.39 cM
• Alliance: Shh^tm2.1Amc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:168522
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exon 2. (J:168522)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Shh Mutation: 48 strains or lines available

References

• Original: J:168522 Huang CC, et al., Progenitor cell expansion and organ size of mouse adrenal is regulated by sonic hedgehog. Endocrinology. 2010 Mar;151(3):1119-28
• All: 1 reference(s)