Fst^tm1Alsc
Targeted Allele Detail

Summary

• Symbol: Fst^tm1Alsc
• Name: follistatin; targeted mutation 1, Alan Schneyer
• MGI ID: MGI:4889199
• Synonyms: FST288
• Gene: Fst Location: Chr13:114588826-114595487 bp, - strand Genetic Position: Chr13, 64.15 cM
• Alliance: Fst^tm1Alsc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:168279
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Hypomorph, Inserted expressed sequence, Modified isoform(s))
• Mutation: Insertion
• Mutation details: A floxed neo cassette with was inserted downstream of exon 5 and a stop codon was inserted after Gln303. The allele is predicted to produce only isoform FST288. (J:168179)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fst Mutation: 19 strains or lines available

References

• Original: J:168179 Kimura F, et al., The follistatin-288 isoform alone is sufficient for survival but not for normal fertility in mice. Endocrinology. 2010 Mar;151(3):1310-9
• All: 5 reference(s)