Tg(CAG-Rpgr)mRDefWrght
Transgene Detail

Summary

• Symbol: Tg(CAG-Rpgr)mRDefWrght
• Name: transgene insertion mRDef, Rachel Wright
• MGI ID: MGI:4936750
• Synonyms: Rpgr^ex1-19
• Transgene: Tg(CAG-Rpgr)mRDefWrght Location: unknown
• Alliance: Tg(CAG-Rpgr)mRDefWrght page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-Rpgr)mRDefWrght expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Rpgr (MGI:1344037)

• Mutation details: The CAG promoter drives expression of a cDNA encoding exons 1 through 19 with an N-terminus 3x-Myc tag. (J:181417)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:181417 Wright RN, et al., Misexpression of the constitutive Rpgr(ex1-19) variant leads to severe photoreceptor degeneration. Invest Ophthalmol Vis Sci. 2011 Jul;52(8):5189-201
• All: 1 reference(s)