Rmi1^{Gt(pUHachi)0283Imeg}
Gene trapped Allele Detail

Summary

• Symbol: Rmi1^{Gt(pUHachi)0283Imeg}
• Name: RecQ mediated genome instability 1; gene trap 0283, Institute of Molecular Embryology and Genetics
• MGI ID: MGI:4936755
• Gene: Rmi1 Location: Chr13:58550062-58558962 bp, + strand Genetic Position: Chr13, 31.05 cM, cytoband B2
• Alliance: Rmi1^{Gt(pUHachi)0283Imeg} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:168271
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector pU-Hachi, which contains a beta-geo cassette, inserted into exon 1. The reduction of transcript expression in heterozygotes was confirmed by RT-PCR. (J:93290, J:168271)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rmi1 Mutation: 35 strains or lines available

References

• Original: J:168271 Suwa A, et al., RMI1 deficiency in mice protects from diet and genetic-induced obesity. FEBS J. 2010 Feb;277(3):677-86
• All: 2 reference(s)