Klkb1^tm1Tigm
Targeted Allele Detail

Summary

• Symbol: Klkb1^tm1Tigm
• Name: kallikrein B, plasma 1; targeted mutation 1, Texas Institute for Genomic Medicine
• MGI ID: MGI:4938303
• Gene: Klkb1 Location: Chr8:45719725-45747872 bp, - strand Genetic Position: Chr8, 25.17 cM, cytoband B1-B3
• Alliance: Klkb1^tm1Tigm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:168556
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ/C neomycin cassette replaced exons 1 and 2. Absense of mRNA was established by PCR analysis. Absence of protein is also reported. (J:168556)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klkb1 Mutation: 40 strains or lines available

References

• Original: J:168556 Liu J, et al., Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein. Nat Med. 2011 Feb;17(2):206-10
• All: 7 reference(s)