Mesd^tm1Bch
Targeted Allele Detail

Summary

• Symbol: Mesd^tm1Bch
• Name: mesoderm development LRP chaperone; targeted mutation 1, Bernadette C Holdener
• MGI ID: MGI:4939501
• Synonyms: Mesdc2^tm1Bch, Mesd^tm1bch
• Gene: Mesd Location: Chr7:83533074-83549519 bp, + strand Genetic Position: Chr7, 48.35 cM
• Alliance: Mesd^tm1Bch page

The Mesd^tm2.1Bch allele does not complement the Mesd^tm1Bch and Tyr^c-3YPSd alleles

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:168622
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 2 and 3 were replaced with a neo cassette. (J:168622)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mesd Mutation: 15 strains or lines available

References

• Original: J:168622 Lighthouse JK, et al., MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm. Dev Dyn. 2011 Mar;240(3):577-88
• All: 2 reference(s)