Rgmb^tm1Hlin
Targeted Allele Detail

Summary

• Symbol: Rgmb^tm1Hlin
• Name: repulsive guidance molecule family member B; targeted mutation 1, Herbert Y Lin
• MGI ID: MGI:4939680
• Gene: Rgmb Location: Chr17:16024923-16051508 bp, - strand Genetic Position: Chr17, 8.96 cM
• Alliance: Rgmb^tm1Hlin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:168909
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The second coding exon was replaced with EGFP, IRES-nls/lacZ, and neo cassette. The absence of transcript expression was confirmed by northern blot and RT-PCR analysis on brain extracts. (J:168909)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rgmb Mutation: 13 strains or lines available

References

• Original: J:168909 Xia Y, et al., Dragon (repulsive guidance molecule B) inhibits IL-6 expression in macrophages. J Immunol. 2011 Feb 1;186(3):1369-76
• All: 4 reference(s)