Lrrk1^tm1.1Mjff
Targeted Allele Detail

Summary

• Symbol: Lrrk1^tm1.1Mjff
• Name: leucine-rich repeat kinase 1; targeted mutation 1.1, The Michael J Fox Foundation
• MGI ID: MGI:4940302
• Synonyms: Lrrk1^tm1.1Youy
• Gene: Lrrk1 Location: Chr7:65908493-66038089 bp, - strand Genetic Position: Chr7, 35.57 cM
• Alliance: Lrrk1^tm1.1Mjff page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:169289
• Parent Cell Line: ART B6-3, B6-3 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector replaced exons 24-29 of the leucine-rich repeat kinase 1 (Lrrk1) gene with a loxP-flanked neomycin resistance (neo) cassette. Cre-mediated recombination removed the neo cassette. (J:169289)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Lrrk1 Mutation: 78 strains or lines available

References

• Original: J:169289 Ouyang Y, Direct Data Submission 2011/03/10. MGI Direct Data Submission. 2011
• All: 4 reference(s)