Tnfrsf14^tm1Csj
Targeted Allele Detail

Summary

• Symbol: Tnfrsf14^tm1Csj
• Name: tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); targeted mutation 1, Choon-Soo Jeong
• MGI ID: MGI:4940320
• Gene: Tnfrsf14 Location: Chr4:155006390-155013020 bp, - strand Genetic Position: Chr4, 85.81 cM
• Alliance: Tnfrsf14^tm1Csj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:169369
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 4.8 kb fragment extending from intron 4 through intron 9 was replaced with a neo cassette. The absence of transcript expression was confirmed by northern blot analysis on bone marrow cells. (J:169369)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnfrsf14 Mutation: 20 strains or lines available

References

• Original: J:169369 Kim WK, et al., Role of TNFR-related 2 mediated immune responses in dextran sulfate sodium-induced inflammatory bowel disease. Mol Cells. 2011 Feb;31(2):99-104
• All: 4 reference(s)