Syt12^tm1.1Sud
Targeted Allele Detail

Summary

• Symbol: Syt12^tm1.1Sud
• Name: synaptotagmin XII; targeted mutation 1.1, Thomas C Sudhof
• MGI ID: MGI:4940391
• Synonyms: Syt12 S97A KI
• Gene: Syt12 Location: Chr19:4495936-4527171 bp, - strand Genetic Position: Chr19, 4.07 cM, cytoband A
• Alliance: Syt12^tm1.1Sud page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:178819
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: Serine 97 (exon 4) was mutated to alanine (S97A) and exons 4-6 were flanked by loxP sites in the targeting vector. An FRT-flanked neomycin cassette was also incorporated. Flp-mediated recombination removed the neo cassette. (J:178819)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Syt12 Mutation: 16 strains or lines available

References

• Original: J:178819 Sudhof TC, Direct Data Submission 2011/03/10. MGI Direct Data Submission. 2012
• All: 2 reference(s)