Ecm1^tm1Bsun
Targeted Allele Detail

Summary

• Symbol: Ecm1^tm1Bsun
• Name: extracellular matrix protein 1; targeted mutation 1, Bing Sun
• MGI ID: MGI:4940879
• Gene: Ecm1 Location: Chr3:95641459-95646880 bp, - strand Genetic Position: Chr3, 40.91 cM
• Alliance: Ecm1^tm1Bsun page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:168252
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 through 11 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on CD4+ T cell subsets. (J:168252)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ecm1 Mutation: 35 strains or lines available

References

• Original: J:168252 Li Z, et al., ECM1 controls T(H)2 cell egress from lymph nodes through re-expression of S1P(1). Nat Immunol. 2011 Feb;12(2):178-85
• All: 3 reference(s)