Nr2c2^tm1Amj
Targeted Allele Detail

Summary

• Symbol: Nr2c2^tm1Amj
• Name: nuclear receptor subfamily 2, group C, member 2; targeted mutation 1, Anton M Jetten
• MGI ID: MGI:4941026
• Gene: Nr2c2 Location: Chr6:92068426-92150039 bp, + strand Genetic Position: Chr6, 41.03 cM
• Alliance: Nr2c2^tm1Amj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:169333
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 6 through 9 were replaced with a neo cassette. (J:169333)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nr2c2 Mutation: 67 strains or lines available

References

• Original: J:169333 Kang HS, et al., Nuclear orphan receptor TAK1/TR4-deficient mice are protected against obesity-linked inflammation, hepatic steatosis, and insulin resistance. Diabetes. 2011 Jan;60(1):177-88
• All: 2 reference(s)