About   Help   FAQ
Adartm1Olds
Targeted Allele Detail
Summary
Symbol: Adartm1Olds
Name: adenosine deaminase, RNA-specific; targeted mutation 1, Michael B A Oldstone
MGI ID: MGI:4941203
Synonyms: Adar1p150-
Gene: Adar  Location: Chr3:89622329-89660753 bp, + strand  Genetic Position: Chr3, 39.19 cM, cytoband F2
Alliance: Adartm1Olds page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:169014
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Modified isoform(s))
Mutations:    Insertion, Intragenic deletion
    Exon 1a was replaced with a floxed neo cassette. This exon is required for isoform p150. (J:169014)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adar Mutation:  72 strains or lines available
References
Original:  J:169014 Ward SV, et al., RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):331-6
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory