Rcan2^tm1Ypt
Targeted Allele Detail

Summary

• Symbol: Rcan2^tm1Ypt
• Name: regulator of calcineurin 2; targeted mutation 1, Ya-ping Tang
• MGI ID: MGI:4941349
• Gene: Rcan2 Location: Chr17:44112243-44350407 bp, + strand Genetic Position: Chr17, 19.77 cM, cytoband C
• Alliance: Rcan2^tm1Ypt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:169558
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: Exon 4 was replaced with a lacZ/neo cassette. The absence of transcript expression was confirmed by northern blot analysis. (J:169558)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rcan2 Mutation: 29 strains or lines available

References

• Original: J:169558 Sun XY, et al., Inactivation of the Rcan2 gene in mice ameliorates the age- and diet-induced obesity by causing a reduction in food intake. PLoS One. 2011;6(1):e14605
• All: 4 reference(s)