Srgap3^tm1.1Ssod
Targeted Allele Detail

Summary

• Symbol: Srgap3^tm1.1Ssod
• Name: SLIT-ROBO Rho GTPase activating protein 3; targeted mutation 1.1, Scott H Soderling
• MGI ID: MGI:4941459
• Gene: Srgap3 Location: Chr6:112694932-112924227 bp, - strand Genetic Position: Chr6, 52.54 cM, cytoband E3
• Alliance: Srgap3^tm1.1Ssod page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:169533
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed exon 3. The absence of protein expression was confirmed by western blot analysis on (J:169533)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Srgap3 Mutation: 62 strains or lines available

References

• Original: J:169533 Carlson BR, et al., WRP/srGAP3 Facilitates the Initiation of Spine Development by an Inverse F-BAR Domain, and Its Loss Impairs Long-Term Memory. J Neurosci. 2011 Feb 16;31(7):2447-60
• All: 2 reference(s)