Lamc3^tm1.1Wjbr
Targeted Allele Detail

Summary

• Symbol: Lamc3^tm1.1Wjbr
• Name: laminin gamma 3; targeted mutation 1.1, William J Brunken
• MGI ID: MGI:4941480
• Synonyms: Lamc3^tm1Wjbr
• Gene: Lamc3 Location: Chr2:31777303-31836551 bp, + strand Genetic Position: Chr2, 21.93 cM, cytoband B
• Alliance: Lamc3^tm1.1Wjbr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:169656
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 2.2 kb fragment spanning exon 1 and part of intron 1 was replaced with an IRES betageo cassette via homologous recombination. The neo selection cassette was removed by mating the heterozygous mouse with a sperm-Cre expressing mouse. (J:169656, J:184380)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lamc3 Mutation: 59 strains or lines available

References

• Original: J:169656 Denes V, et al., Laminin deficits induce alterations in the development of dopaminergic neurons in the mouse retina. Vis Neurosci. 2007 Jul-Aug;24(4):549-62
• All: 7 reference(s)