Tg(Thy1-QPCT)#Tbay
Transgene Detail

Summary

• Symbol: Tg(Thy1-QPCT)#Tbay
• Name: transgene insertion, Thomas A Bayer
• MGI ID: MGI:4941713
• Synonyms: hQC
• Transgene: Tg(Thy1-QPCT)#Tbay Location: unknown
• Alliance: Tg(Thy1-QPCT)#Tbay page

Transgene origin

• Strain of Origin: C57BL/6J x CBA

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Thy1-QPCT)#Tbay expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  QPCT (25797)

  Qpct	(MGI:1917786)

• Mutation details: The mouse promoter is used to drive the human cDNA. No line snames or symbols were provided. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:169481)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:169481 Jawhar S, et al., Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate A{beta} formation, induces behavioral deficits, and glutaminyl cyclase knock-out rescues the behavioral phenotype in 5XFAD mice. J Biol Chem. 2011 Feb 11;286(6):4454-60
• All: 1 reference(s)