Arid3a^tm1Pwt
Targeted Allele Detail

Summary

• Symbol: Arid3a^tm1Pwt
• Name: AT-rich interaction domain 3A; targeted mutation 1, Philip W Tucker
• MGI ID: MGI:4941793
• Gene: Arid3a Location: Chr10:79762877-79790852 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Arid3a^tm1Pwt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:197237
• Parent Cell Line: SM1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1 through 7 were replaced with a neo cassette. The absence of transcript expression was confirmed by RT-PCR on fetal liver and adult splenic B cells. (J:169178)

Expression

In Mice Carrying this Mutation:	61 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arid3a Mutation: 20 strains or lines available

References

• Original: J:197237 An G, et al., Loss of Bright/ARID3a function promotes developmental plasticity. Stem Cells. 2010 Sep;28(9):1560-7
• All: 3 reference(s)