Selenok^tm1.2Itl
Targeted Allele Detail

Summary

• Symbol: Selenok^tm1.2Itl
• Name: selenoprotein K; targeted mutation 1.2, inGenious Targeting Laboratory
• MGI ID: MGI:4941878
• Synonyms: Selk^tm1.2Igl
• Gene: Selenok Location: Chr14:29690337-29697031 bp, + strand Genetic Position: Chr14, 18.36 cM
• Alliance: Selenok^tm1.2Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:169169
• Parent Cell Line: iTL IC1 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exons 2 and 3. (J:169169)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Selenok Mutation: 15 strains or lines available

References

• Original: J:169169 Verma S, et al., Selenoprotein K knockout mice exhibit deficient calcium flux in immune cells and impaired immune responses. J Immunol. 2011 Feb 15;186(4):2127-37
• All: 7 reference(s)