Adora2b^tm1.1Msit
Targeted Allele Detail

Summary

• Symbol: Adora2b^tm1.1Msit
• Name: adenosine A2b receptor; targeted mutation 1.1, Michail Sitkovsky
• MGI ID: MGI:4941886
• Gene: Adora2b Location: Chr11:62139810-62157278 bp, + strand Genetic Position: Chr11, 37.96 cM, cytoband B2
• Alliance: Adora2b^tm1.1Msit page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:169155
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exon 2. (J:169155)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adora2b Mutation: 20 strains or lines available

References

• Original: J:169155 Belikoff BG, et al., A2B adenosine receptor blockade enhances macrophage-mediated bacterial phagocytosis and improves polymicrobial sepsis survival in mice. J Immunol. 2011 Feb 15;186(4):2444-53
• All: 6 reference(s)