Prickle1^m2Ingm
Chemically induced Allele Detail

Summary

• Symbol: Prickle1^m2Ingm
• Name: prickle planar cell polarity protein 1; mutation 2, Ingenium Pharmaceuticals
• MGI ID: MGI:4941929
• Synonyms: Cys251X, Prickle1^C251X
• Gene: Prickle1 Location: Chr15:93396995-93493772 bp, - strand Genetic Position: Chr15, 47.69 cM
• Alliance: Prickle1^m2Ingm page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Nucleotide substitutions
• Mutation details: ENU mutagenesis induced the amino acid substitution of a stop codon for cysteine at position 251 (C251X). (J:169136)

Expression

In Mice Carrying this Mutation:	57 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Prickle1 Mutation: 34 strains or lines available

References

• Original: J:169136 Tao H, et al., Mutations in prickle orthologs cause seizures in flies, mice, and humans. Am J Hum Genet. 2011 Feb 11;88(2):138-49
• All: 5 reference(s)