Axin1^tm1.1Dic
Targeted Allele Detail

Summary

• Symbol: Axin1^tm1.1Dic
• Name: axin 1; targeted mutation 1.1, Di Chen
• MGI ID: MGI:4941940
• Synonyms: Axin1^flox, Axin1^fx
• Gene: Axin1 Location: Chr17:26357662-26414785 bp, + strand Genetic Position: Chr17, 13.07 cM
• Alliance: Axin1^tm1.1Dic page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:169694
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 5' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette, leaving exon 2 floxed. (J:169694)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Axin1 Mutation: 44 strains or lines available

References

• Original: J:169694 Xie R, et al., Generation of Axin1 conditional mutant mice. Genesis. 2011 Feb;49(2):98-102
• All: 2 reference(s)