Zic2^m1Nisw
Chemically induced Allele Detail

Summary

• Symbol: Zic2^m1Nisw
• Name: zinc finger protein of the cerebellum 2; mutation 1, Lee Niswander
• MGI ID: MGI:4943187
• Synonyms: Line7-12
• Gene: Zic2 Location: Chr14:122712847-122717264 bp, + strand Genetic Position: Chr14, 65.97 cM
• Alliance: Zic2^m1Nisw page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Hypomorph)
• Mutation: Nucleotide substitutions
• Mutation details: ENU mutagenesis induced A to T transversion at position 986 (A986T) that changes glutamic acid to valine in the zinc finger domain. The protein level is not affected in this hypomorphic allele. (J:169832, J:214510)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zic2 Mutation: 41 strains or lines available

References

• Original: J:169832 Niswander L, Direct Data Submission 2011/03/29. MGI Direct Data Submission. 2011
• All: 3 reference(s)