Zbtb7b^tm1.1Skok
Targeted Allele Detail

Summary

• Symbol: Zbtb7b^tm1.1Skok
• Name: zinc finger and BTB domain containing 7B; targeted mutation 1.1, Jane A Skok
• MGI ID: MGI:4943529
• Synonyms: Zbtb7b^hd
• Gene: Zbtb7b Location: Chr3:89284953-89300976 bp, - strand Genetic Position: Chr3, 39.09 cM, cytoband A1-A2
• Alliance: Zbtb7b^tm1.1Skok page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:169841
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutations: Insertion, Single point mutation
• Mutation details: A floxed neo cassette was inserted upstream of the coding region. An A to G transition was inserted into exon 2 (the first coding exon) giving rise to an R389G mutation. Cre-mediated recombination removed the neo cassette. (J:169841)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zbtb7b Mutation: 26 strains or lines available

References

• Original: J:169841 Collins A, et al., RUNX Transcription Factor-Mediated Association of Cd4 and Cd8 Enables Coordinate Gene Regulation. Immunity. 2011 Mar 25;34(3):303-14
• All: 1 reference(s)