Tdrd7^nmf166
Chemically induced Allele Detail

Summary

• Symbol: Tdrd7^nmf166
• Name: tudor domain containing 7; neuroscience mutagenesis facility, 166
• MGI ID: MGI:4943539
• Synonyms: NMF166, Tdrd7^glcr5, Tdrd7^grm5
• Gene: Tdrd7 Location: Chr4:45965334-46034761 bp, + strand Genetic Position: Chr4, 24.48 cM
• Alliance: Tdrd7^nmf166 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU induced a C to T nonsense mutation at position 2187 in the coding region resulting in glutamine to stop mutation at amino acid 723. Western blot analysis did not detect any protein expression in the eyes from homozygous mice indicating this is a null allele. (J:68708, J:169836)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tdrd7 Mutation: 43 strains or lines available

References

• Original: J:87349 JAX Neuroscience Mutagenesis Facility, Heritable mouse mutants from JAX NMF ENU Mutagenesis Program. MGI Direct Data Submission. 2004-7
• All: 3 reference(s)