Thoc5^tm1Tate
Targeted Allele Detail

Summary

• Symbol: Thoc5^tm1Tate
• Name: THO complex 5; targeted mutation 1, Teruko Tamura
• MGI ID: MGI:4946267
• Synonyms: THOC5/FMIP floxed
• Gene: Thoc5 Location: Chr11:4845339-4878867 bp, + strand Genetic Position: Chr11, 3.09 cM
• Alliance: Thoc5^tm1Tate page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:169944
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted upstream of exon 4. A loxP site was inserted downstream of exon 5. (J:169944)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Thoc5 Mutation: 48 strains or lines available

References

• Original: J:169944 Mancini A, et al., THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo. BMC Biol. 2010;8:1
• All: 4 reference(s)