Del(2Cd59b-Cd59a)1Jha
Targeted Allele Detail

Summary

• Symbol: Del(2Cd59b-Cd59a)1Jha
• Name: deletion, Chr 2, Jose A Halperin 1
• MGI ID: MGI:4947111
• Synonyms: Cd59a/Cd59b^tm1Jha, Del1Jha, mCd59ab^-
• Gene: Del(2Cd59b-Cd59a)1Jha Location: unknown Genetic Position: Chr2, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:170754
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(2Cd59b-Cd59a)1Jha involves 2 genes/genome features (Cd59b, Cd59a) View all
• Mutation details: A neo cassette replaced exons 1 and 2 of Cd59a and exon 4 of Cd59b. The absence of either protein was confirmed by FACS analysis on platelets. (J:170754)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(2Cd59b-Cd59a)1Jha Mutation: 0 strains or lines available

References

• Original: J:170754 Qin X, et al., Generation and phenotyping of mCd59a and mCd59b double-knockout mice. Am J Hematol. 2009 Feb;84(2):65-70
• All: 3 reference(s)