Kat7^tm1.1Avo
Targeted Allele Detail

Summary

• Symbol: Kat7^tm1.1Avo
• Name: K(lysine) acetyltransferase 7; targeted mutation 1.1, Anne K Voss
• MGI ID: MGI:4947690
• Synonyms: Hbo1^loxP
• Gene: Kat7 Location: Chr11:95165085-95201072 bp, - strand Genetic Position: Chr11, 59.01 cM
• Alliance: Kat7^tm1.1Avo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:170405
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 1. Flp-mediated recombination removed the neo cassette leaving exon 1 floxed. (J:170405)

Expression

In Mice Carrying this Mutation:

23 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kat7 Mutation: 150 strains or lines available

References

• Original: J:170405 Kueh AJ, et al., HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development. Mol Cell Biol. 2011 Feb;31(4):845-60
• All: 4 reference(s)