Kat7^tm1.2Avo
Targeted Allele Detail

Summary

• Symbol: Kat7^tm1.2Avo
• Name: K(lysine) acetyltransferase 7; targeted mutation 1.2, Anne K Voss
• MGI ID: MGI:4947692
• Gene: Kat7 Location: Chr11:95165085-95201072 bp, - strand Genetic Position: Chr11, 59.01 cM
• Alliance: Kat7^tm1.2Avo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:170405
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed exon 1. The absence of transcript expression was confirmed with in situ hybridization on E9.5 embryos. (J:170405)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kat7 Mutation: 150 strains or lines available

References

• Original: J:170405 Kueh AJ, et al., HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development. Mol Cell Biol. 2011 Feb;31(4):845-60
• All: 1 reference(s)