Bglap/Bglap2^tm3.1Kry
Targeted Allele Detail

Summary

• Symbol: Bglap/Bglap2^tm3.1Kry
• Name: bone gamma-carboxyglutamate protein 2; targeted mutation 3.1, Gerard Karsenty
• MGI ID: MGI:4949089
• Synonyms: Ocn-Floxed
• Gene: Bglap2 Location: Chr3:88285043-88286006 bp, - strand Genetic Position: Chr3, 38.81 cM
• Alliance: Bglap/Bglap2^tm3.1Kry page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:170888
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted into the Bglap coding region. An FRT-flanked neo cassette with a 5' loxP site was inserted downstream of Bglap2 coding region. Flp-metiated recombination removed the neo cassette. (J:170888)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bglap2 Mutation: 9 strains or lines available

References

• Original: J:170888 Oury F, et al., Endocrine regulation of male fertility by the skeleton. Cell. 2011 Mar 4;144(5):796-809
• All: 3 reference(s)