Gprc6a^tm1.1Kry
Targeted Allele Detail

Summary

• Symbol: Gprc6a^tm1.1Kry
• Name: G protein-coupled receptor, family C, group 6, member A; targeted mutation 1.1, Gerard Karsenty
• MGI ID: MGI:4949090
• Synonyms: Gprc6a^f
• Gene: Gprc6a Location: Chr10:51490919-51507554 bp, - strand Genetic Position: Chr10, 25.66 cM
• Alliance: Gprc6a^tm1.1Kry page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:170888
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette, leaving exon 2 floxed. (J:170888)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gprc6a Mutation: 67 strains or lines available

References

• Original: J:170888 Oury F, et al., Endocrine regulation of male fertility by the skeleton. Cell. 2011 Mar 4;144(5):796-809
• All: 9 reference(s)