About   Help   FAQ
Snx27tm1Lslo
Targeted Allele Detail
Summary
Symbol: Snx27tm1Lslo
Name: sorting nexin family member 27; targeted mutation 1, Li Shen Loo
MGI ID: MGI:4949192
Gene: Snx27  Location: Chr3:94404851-94490023 bp, - strand  Genetic Position: Chr3, 40.74 cM, cytoband F2
Alliance: Snx27tm1Lslo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171001
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neo cassette was inserted into exon 3. The absence of protein expression was confirmed by western blot analysis on kidney and brain extracts. (J:171001)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Snx27 Mutation:  25 strains or lines available
References
Original:  J:171001 Cai L, et al., Deficiency of Sorting Nexin 27 (SNX27) Leads to Growth Retardation and Elevated Levels of N-Methyl-D-Aspartate Receptor 2C (NR2C). Mol Cell Biol. 2011 Apr;31(8):1734-47
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory